GOAT ANTI ATP5A1

Goat anti Human ATP5A1 antibody recognizes ATP5A1, also known as ATP synthase subunit alpha mitochondrial, non-cardiac muscle-like 2, ATP sythase (F1-ATPase) alpha subunit, epididymis secretory sperm binding protein Li 123m or mitochondrial ATP synthetase, oligomycin-resistant.

The ATP5A1 gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5A1 gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoforms have been identified. Pseudogenes of ATP5A1 are located on chromosomes 9, 2, and 16 (provided by RefSeq, Mar 2012).

Goat anti Human ATP5A1 antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.