GOAT ANTI CD49a

Goat anti Human CD49a antibody recognizes CD49a also known as integrin alpha-1, CD49 antigen-like family member A, VLA-1, ITGA1, laminin and collagen receptor or very late activation protein 1.

ITGA1 gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted von Willebrand factor type I domain which is thought to be involved in collagen binding (provided by RefSeq, Jul 2008).

Goat anti Human CD49a antibody detects a band of 150 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.