RABBIT ANTI BMP-7

Rabbit anti Human BMP-7 antibody recognizes the bone morphogenetic protein 7, also known as osteogenic protein 1 (OP-1).

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by BMP7 has a proposed role in early development and possible bone inductive activity (provided by RefSeq, Jul 2008).

Rabbit anti Human BMP-7 antibody detects a band of 49 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.