RABBIT ANTI CAPZB

Rabbit anti Human CAPZB antibody recognizes CAPZB also known as F-actin-capping protein subunit beta or capZ beta.

The CAPZB gene encodes the beta subunit of the barbed-end actin binding protein, which belongs to the F-actin capping protein family. The capping protein is a heterodimeric actin capping protein that blocks actin filament assembly and disassembly at the fast growing (barbed) filament ends and functions in regulating actin filament dynamics as well as in stabilizing actin filament lengths in muscle and nonmuscle cells. A pseudogene of CAPZB is located on the long arm of chromosome 2. Multiple alternatively spliced transcript variants encoding different isoforms have been found (provided by RefSeq, Aug 2013).

Rabbit anti Human CAPZB antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.