RABBIT ANTI CARBONIC ANHYDRASE III

Rabbit anti Human carbonic Anhydrase III antibody recognizes carbonic anhydrase III, also known as CA3, CA-III, HEL-S-167mP, carbonate dehydratase III or epididymis secretory sperm binding protein Li 167mP.

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns (provided by RefSeq, Oct 2008).

Rabbit anti Human carbonic anhydrase III antibody detects a band of 29 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.