RABBIT ANTI CYTOCHROME P450 AROMATASE

Rabbit anti Human cytochrome P450 aromatase antibody recognizes cytochrome P450 aromatase, also known as CYP450 family 26 subfamily B member, cytochrome P450 retinoid metabolizing protein or cytochrome P450, family 26, subfamily B, polypeptide 1.

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants (provided by RefSeq, Apr 2013).

Rabbit anti Human cytochrome P450 aromatase antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.