RABBIT ANTI DDX5

Rabbit anti Human DDX5 antibody recognizes DDX5, also known as HLR1, G17P, HUMP68 or DEAD-box helicase 5.

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants (provided by RefSeq, Feb 2016).

Rabbit anti Human DDX5 antibody detects a band of 62 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.