RABBIT ANTI DJ-1

Rabbit anti Human DJ-1 antibody recognizes the oncogene DJ-1, also known as Parkinson disease (autosomal recessive, early onset) 7, PARK-7 and epididymis secretory sperm binding protein Li 67p

Encoded by the PARK7 gene, oncogene DJ-1 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in PARK7 gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for PARK7 (provided by RefSeq, Jul 2008).

Rabbit anti Human DJ-1 antibody detects a band of 22 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.