RABBIT ANTI FATTY ACID SYNTHASE

Rabbit anti Human fatty acid synthase antibody recognizes fatty acid synthase, also known as FASN, FAS and short chain dehydrogenase/reductase family 27X, member 1.

The enzyme encoded by the fatty acid synthase gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha (provided by RefSeq, Jul 2008).

Rabbit anti Human fatty acid synthase antibody detects a band of 273 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.