RABBIT ANTI FUSE-BINDING PROTEIN 1

Rabbit anti Human FUSE-binding protein 1 antibody recognizes the far upstream element (FUSE)-binding protein 1, also known as DNA helicase V and hDH V.

Encoded by the FUBP1 gene, FUSE-binding protein 1 is a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase (provided by RefSeq, Jul 2008).

Rabbit anti Human FUSE-binding protein 1 antibody detects a band of 77 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.