RABBIT ANTI GGA3

Rabbit anti Human GGA3 antibody recognizes GGA3, also known as ADP-ribosylation factor-binding protein GGA3 or Golgi-localized, gamma ear-containing, ARF-binding protein 3.

The GGA3 gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in GGA3 (provided by RefSeq, Feb 2010).

Rabbit anti Human GGA3 antibody detects a band of 90 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.