RABBIT ANTI HEAT SHOCK PROTEIN 60

Rabbit anti Human heat shock protein 60 antibody recognizes heat shock protein 60 also known as 60 kDa chaperonin, HSPD1, HSP60, GROEL and mitochondrial matrix protein P1.

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13 (provided by RefSeq, Jun 2010).

Rabbit anti Human heat shock protein 60 antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.