RABBIT ANTI HEC1

Rabbit anti Human HEC1 antibody recognizes the kinetochore protein NDC80 homolog, also known as kinetochore complex component, HEC1, kinetochore associated 2, kinetochore protein Hec1 or retinoblastoma-associated protein HEC.

The NDC80 gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. (provided by RefSeq, Oct 2011).

Rabbit anti Human HEC1 antibody detects a band of 76 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.