RABBIT ANTI HEMOGLOBIN SUBUNIT EPSILON

Rabbit anti Human hemoglobin subunit epsilon antibody recognizes hemoglobin subunit epsilon also known as epsilon globin.

The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' (provided by RefSeq, Jul 2008).

Rabbit anti Human hemoglobin subunit epsilon antibody detects a band of 14 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.