RABBIT ANTI MYOSIN HEAVY CHAIN 9

Rabbit anti Human myosin heavy chain 9 antibody recognizes myosin heavy chain 9, also known as cellular myosin heavy chain, type A, myosin-9, non-muscle myosin heavy chain A, non-muscle myosin heavy chain IIa, non-muscle myosin heavy polypeptide 9 and nonmuscle myosin heavy chain II-A.

Encoded by the MYH9 gene, myosin heavy chain 9 (myosin-9) is a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). This protein contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness (provided by RefSeq, Dec 2011).

Rabbit anti Human myosin heavy chain 9 antibody detects a band of 227 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.