RABBIT ANTI N-Myc

Rabbit anti Human N-Myc antibody recognizes N-Myc, also known as v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog, class E basic helix-loop-helix protein 37, neuroblastoma MYC oncogene, neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene and oncogene NMYC, pp65/67.

The MYCN gene is a member of the MYC family and encodes N-Myc, a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of MYCN is associated with a variety of tumors, most notably neuroblastomas (provided by RefSeq, Jul 2008).