Rabbit anti Human NPEPPS antibody recognizes puromycin-sensitive aminopeptidase, also known as cytosol alanyl aminopeptidase, AAP-S or metalloproteinase MP100.
The NPEPPS gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular membranes. This enzyme degrades enkaphalins in the brain, and studies in mouse suggest that it is involved in proteolytic events regulating the cell cycle (provided by RefSeq, Jul 2008).
Rabbit anti Human NPEPPS antibody detects a band of 103 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
