Rabbit anti Human PC4 antibody recognizes the activated RNA polymerase II transcriptional coactivator p15, also known as activated RNA polymerase II transcription cofactor 4, or positive cofactor 4.
This protein forms a homodimer and is aneneral coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. It also may be involved in stabilizing the multiprotein transcription complex. SUB1 in vivo binds single stranded DNA, but in vitro, it binds non-specifically to double-stranded DNA (ds DNA).
Rabbit anti Human PC4 antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
