RABBIT ANTI PEROXIREDOXIN 2

Rabbit anti Human peroxiredoxin 2 antibody recognizes peroxiredoxin 2, also known as epididymis secretory sperm binding protein Li 2a, natural killer cell-enhancing factor B, thiol-specific antioxidant 1, thioredoxin peroxidase 1, thioredoxin-dependent peroxide reductase 1 and torin.

Peroxiredoxin 2 is member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. This protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of the protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making Peroxiredoxin 2 a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13 (provided by RefSeq, Mar 2013).

Rabbit anti Human peroxiredoxin 2 antibody detects a band of 22 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.