RABBIT ANTI PPP2R2A

Rabbit anti Human PPP2R2A antibody recognizes PPP2R2A, also known as protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52) alpha isoform, 55 kDa regulatory subunit B, alpha isoform and serine/threonine-protein phosphatase 2A.

The product of the PPP2R2A gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, which associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. The PPP2R2A gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described (provided by RefSeq, Apr 2010).

Rabbit anti Human PPP2R2A antibody detects a band of 52 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.