RABBIT ANTI RAB7A

Rabbit anti Human RAB7A antibody recognizes the Ras-related protein Rab-7a, also known as RAB7 or Ras-associated protein RAB7.

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. RAB7A encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in RAB7A have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies (provided by RefSeq, Jul 2008).

Rabbit anti Human RAB7A antibody detects a band of 23 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.