RABBIT ANTI SFRP1

Rabbit anti Human SFRP1 antibody recognizes SFRP1, also known as SARP-2, secreted frizzled-related protein 1 or simply secreted apoptosis-related protein 2.
The SFRP1 gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. SFRP1 may also be involved in determining the polarity of photoreceptor cells in the retina (provided by RefSeq, Sep 2009).
Rabbit anti Human SFRP1 antibody detects a band of 35 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Disponibilidad | Bajo pedido |
---|---|
Ref Dutscher | D6VPA00336 |
Marca | BIO-RAD |
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