RABBIT ANTI SUPEROXIDE DISMUTASE (Mn)

Rabbit anti Human superoxide dismutase (Mn) recognizes superoxide dismutase (Mn), also known as superoxide dismutase 2, SOD2, Mn superoxide dismutase, indophenoloxidase B, manganese-containing superoxide dismutase or mangano-superoxide dismutase.

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1 (provided by RefSeq, Apr 2016).

Rabbit anti Human superoxide dismutase (Mn) detects a band at 22 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.