RABBIT ANTI TUBULIN ALPHA 4A CHAIN

Rabbit anti Human tubulin alpha 4A chain antibody recognizes tubulin alpha 4A chain, also known as tubulin H2-alpha, tubulin alpha-1 chain, and tubulin, alpha 1 (testis specific).

Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. Encoded by the TUBA4A gene, tubulin alpha 4A chain is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for TUBA4A (provided by RefSeq, Jun 2013).

Rabbit anti Human tubulin alpha 4A chain antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.