The Edit-R algorithm's alignment tool identifies mismatches AND gaps to optimize selection of highly specific target sequences; and
The Edit-R algorithm scores were developed on functional gene knockout rather than just quantifying indels in the genomic target DNA.
Pre-designed Edit-R Lentiviral sgRNAs are supplied as glycerol stocks and as concentrated high-titer particles for straightforward delivery into Cas9-expressing cells for efficient knockout without need for cloning or packaging. Purified, concentrated lentiviral particles can be directly transduced into difficult-to-transfect cells without the toxic cellular debris and contaminants found in supernatant preparations.Glycerol stocks can be grown and the expression plasmid purifed for immediate transfection or packaging into particles.
Save money by eliminating time-consuming cloning, packaging and titering steps
High-quality, concentrated, purified lentiviral particles for direct transduction with minimal cytotoxicity
Pre-designed sgRNA generated using the Edit-R CRISPR RNA algorithm for unparalleled specificity and functionality
Caracteristicas
Genome-wide single guide RNAs for efficient gene knockout & unparalleled specificity; available as glycerol stocks and high-titer purified particles
